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Nerve Clues: New Research on Mice May Help Understand Pain

Research being conducted at the Institute for Basic Biomedical Science at the Johns Hopkins School of Medicine is bringing scientists closer to understanding the mechanics of sensory nerves. Advanced techniques have allowed the researchers to map the skin nerves of mice and the results, along with molecular and neurological information, could help scientists and doctors better understand all forms of sensory input – including pain.

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Hope for People with Morphine Hypersensitivity

If you’ve ever taken morphine only to have your pain increase, then you may suffer from morphine hypersensitivity. For those suffering from chronic pain, it can be terrible and despairing to find out that morphine only makes your pain worse. But there is new research being conducted which is revealing how morphine hypersensitivity works, offering new hope to people who experience it.

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Tip Sheet: Neuropathic Face Pain and Trigeminal Neuralgia

All tips are in the patient’s own words. These tips are anecdotal only and are not endorsed by TNA. They are intended for information purposes only, to supplement a visitor’s general knowledge. It is not intended to replace or in any way supplement or qualify the services of a qualified medical professional and/or other appropriate […]

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Striking Back! The Trigeminal Neuralgia and Face Pain Handbook

Published by TNA and written by Joanna Zakrzewska, Professor of Pain in relation to Oral Medicine and an Honorary Consultant at the Institute of Dentistry, Barts and the London, Queen Mary’s School of Medicine and Dentistry, University oPublished by TNA and written by George Weigel and Kenneth F. Casey, M.D., is written in layman’s terms, describes all aspects of TN and provides information and resources for patients, family, and medical professionals.

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Pain-Triggering and Pain-Safe Foods

Even with drugs, surgery, complementary therapies, and more, facial neuralgia patients often report that they still have pain that is triggered by certain activities, environmental conditions, and food. Although there have been no specific dietary studies on neuropathic facial pain, it seems to make good sense to cut back on anything that stimulates the central nervous system. The last thing you want to do is further excite an already hyper-excited trigeminal nerve.

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Neuropathic Facial Pain, Vitamin B-12 & Myelin

If damaged myelin is at the heart of the trigeminal nerve’s short-circuiting pain, then fixing it seems to be a logical goal. Neurosurgeons address this problem by seeking to move a blood vessel away from the area where the vessel is hitting the nerve as blood pumps through it and consequently wears down the myelin sheath.

The nutritional approach encourages the body to heal injured myelin. Because Vitamin B-12 is thought to play a role in myelin production, it is one of the most common nutrients used in trying to combat TN and neuropathic facial pain.

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Trigeminal Neuralgia (TN) and Multiple Sclerosis (MS)

TN may rarely be the first symptom of MS, but usually does not begin until about 11 years after the onset of MS.
When TN is diagnosed in anyone under the age of 40, MS is suspected and should be ruled out.
TN with MS is 18% more likely to be bilateral. It usually begins on one side and after years occurs on the other. It is preferable to treat each side individually, while guarding against having numbness on both sides.
TN with MS is more likely to be atypical pain – dull, burning & constant rather than electric bolt type pain.
1-2% of MS patients develop TN.

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Visting the Dentist: Tips for Facial Pain Patients

Tips for staying as painless as possible during dental treatment. Patients suffering from face pain, including TN (Trigeminal Neuralgia) are often concerned that dental procedures will aggravate their pain. TN patients who are pain free are at little or no risk, yet they still fear work within their mouth. Dental work is hardest on those with constant neuropathic facial pain.

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Anesthesia Dolorosa

What is Anesthesia Dolorosa (AD)? The cause of AD. Why AD occurs. What the pain of AD feels like. Why it’s important to distinguish the difference between AD and TN. Treatments for AD.

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